Distinctive Qualities
of Mesenchymal Stem Cells

• Holds promise to rectify enzyme defects in genetic disorders.

• Easily isolated from diverse tissues and multiplied in lab settings.

• Demonstrates both immunomodulatory and immunosuppressive capabilities.

• Ensures minimal side effects and poses no major adverse reactions.

• Compatible for allogenic use without triggering immune rejection.

• Innate resilience and adaptability, ideal for gene therapy endeavors.

Although there are many sources of mesenchymal stem cells in the body, the sources of MSCs we use are:

Mesenchymal Stem Cell from Bone Marrow

Mesenchymal Stem Cell from Adipose Tissue

Synovial Origin Mesenchymal Stem Cell

Mesenchymal Stem Cell from Cord Matrix

Synovial Origin Mesenchymal Stem Cell

The synovium, a unique mesenchymal tissue, lines the inner surfaces of joints, bursae, and tendon sheaths within our movement system. Mesenchymal stem cells sourced from the synovium play a pivotal role in the regeneration of cartilage and the meniscus.

Uses of Mesenchymal Stem Cells in Orthopedics

• Contributes to bone formation through osteoblastic activity.

• Displays high osteogenic activity in areas with osteonecrosis.

• Aids in type-1 collagen production, osteoblastic differentiation, and increases bone mineral density in osteogenesis imperfecta.

• Facilitates better bone union and fusion, improving by up to 80%, in cases of vertebral fractures.

• Assists in full-thickness cartilage formation through chondrogenic and osteogenic differentiation in diseases causing significant cartilage damage, such as rheumatoid arthritis, senile osteoarthritis, hemophilic arthropathy, reactive arthritis, and osteochondritis dissecans.

• Enhances healing rates of avascular peripheral meniscus tears.

• Demonstrates rapid recovery and reduces rerupture rates in tendon damage repair.

Mesenchymal Stem Cell Membrane and Its Applications:

Derived from sources such as the umbilical cord, adipose tissue, and bone marrow, mesenchymal stem cells can be integrated into a membrane primarily made up of type-1 and type-3 collagen. This specially crafted membrane acts as a therapeutic patch, promoting tissue regeneration. Once applied, these cells adapt and differentiate based on the unique signals from the targeted area. Potential applications for this mesenchymal stem cell membrane include: