FIBROBLAST

FIBROBLAST

Fibroblast Application

Fibroblasts, the predominant cells in connective tissue, have pivotal roles in skin health. Their primary function is producing essential skin components like collagen, elastin proteins, and hyaluronic acid, which impart radiance and elasticity to the skin. A decline in fibroblast count, or the elements they produce, can lead to structural skin anomalies and the emergence of aging signs.

Fibroblast cells, which are cultured from the patient's own skin tissue, perform the following functions:

  • Produce the proteins and growth factors that the skin needs.

  • Suppress any inflammation that has occurred for any reason with their anti-inflammatory properties.

  • Reduce signs of aging in the skin.

  • Play a role in wound healing.

How is Fibroblast Applied?

  • A minimally invasive punch biopsy is used to collect a tissue sample about 3 mm in diameter from the patient, using local anesthesia.

  • Ideal sample collection sites include sun-protected and aesthetically non-disruptive areas, such as behind the ear, the inner arm, or the groin.

  • The biopsy procedure ensures patient comfort with minimal discomfort.

  • Once collected, the sample is secured in our specialized kit and swiftly dispatched to our lab within 24 hours, maintaining a cold chain.

  • In our state-of-the-art laboratory, which adheres to cGMP guidelines and holds a production permit from the Ministry of Health, the tissue is processed to commence fibroblast production. By week's end, a robust count of 100 million cells is readied for transplantation.

  • Post comprehensive quality checks, the final fibroblast product is made available in sterile vials, optimized for injection.

  • The application involves precise mesotherapy injections using a fine 26G injector, targeting areas such as around the eyes, lips, forehead, jawline, hands, and décolletage.

  • Depending on the physician's recommendation, a 3-dose treatment regimen is followed, with doses spaced 2-6 weeks apart.

  • Each treatment utilizes approximately 30 million fibroblast cells.

  • For future treatments, surplus fibroblast cells are cryogenically preserved in vapor phase nitrogen tanks at -196°C at our facility, ensuring their vitality for subsequent doses.

Suggestions Related to the Application

- Fibroblast treatment is long-term. However, this period is affected by factors such as the individual's quality of life, tobacco and alcohol use, stress factors, skin type, water consumption, age, genetic structure, facial expressions, and external factors such as UV.

- Exposure to excessive sun should be avoided after the treatment.

- Cold compresses can be made with the help of an ice pack on the day of treatment.